#17
Published in Biostatistics, 2025
Citation: P.E. Sugier, Y. Asgari, M. Sedki, T. Truong, B. Liquet, (2025). "Meta-analysis models with group structure for pleiotropy detection at gene and variant level using summary statistics from multiple datasets. 26(1), kxaf037 https://academic.oup.com/biostatistics/article-abstract/26/1/kxaf037/8324642?redirectedFrom=fulltext
In this study, we propose a new approach called MPSG (Meta-analysis model adapted for Pleiotropy Selection with Group structure) which performs a penalized multivariate meta-analysis method adapted for pleiotropy and takes into account the group structure information nested in the data to select relevant variants and genes (or pathways) from all the genetic information.
P.E. Sugier, Y. Asgari, M. Sedki, T. Truong, B. Liquet, (2025). "Meta-analysis models with group structure for pleiotropy detection at gene and variant level using summary statistics from multiple datasets" Biostatistics. 26(1), kxaf037.