#12

Published in Scientific Reports, 2020

Citation: H. Rakhsh-Khorshid1, H. Samimi, S. Torabi, S.M. Sajjadi-Jazi, H. Samadi, F. Ghafouri, Y. Asgari, V. Haghpanah, (2020). "Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma" Scientific Reports. Vol 10, 21440 https://link.springer.com/content/pdf/10.1038/s41598-020-78574-x.pdf

In this paper, we have used a systems biology approach to find more suitable targets in order to restore sodium-iodide symporter (NIS) expression in ATC cells. We have built a simplified protein interaction network including transcription factors and proteins involved in signaling pathways which regulate NIS expression.

Download paper here

H. Rakhsh-Khorshid1, H. Samimi, S. Torabi, S.M. Sajjadi-Jazi, H. Samadi, F. Ghafouri, Y. Asgari, V. Haghpanah, (2020). “Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma” Scientific Reports. Vol 10, 21440.